IV Cocaine Abuse: A Laboratory Model - 1
Phase 2
Completed
- Conditions
- Cocaine-Related Disorders
- Registration Number
- NCT00000212
- Lead Sponsor
- New York State Psychiatric Institute
- Brief Summary
The purpose of this study is to evaluate the effects of desipramine DMI maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effects of DMI on cocaine craving Amount cocaine self-administered Drug use during outpatient DMI maintenance Direct cocaine effects (cardiovascular, subjective Interaction of cocaine and DMI on cardio measures Interaction of cocaine/DMI on coc's subjective
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie desipramine's effect on cocaine craving and relapse prevention?
How does desipramine compare to standard-of-care antidepressants in treating cocaine use disorders?
Are there specific biomarkers that predict response to desipramine in cocaine addiction treatment?
What are the potential adverse events associated with desipramine maintenance for cocaine abuse?
What combination therapies have been explored with desipramine for substance use disorders?
Trial Locations
- Locations (1)
Columbia University
🇺🇸New York, New York, United States
Columbia University🇺🇸New York, New York, United States