Evaluation of a Desipramine Ceiling in Cocaine Abuse - 1
Phase 2
Completed
- Conditions
- Substance-Related DisordersCocaine-Related Disorders
- Registration Number
- NCT00000245
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Brief Summary
The purpose of this study is to confirm whether a blood level ""ceiling"" exists on desipramine effect in cocaine abuse.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Craving Cocaine use Retention Anxiety Mood indicators Depression
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
Does desipramine exhibit a maximum blood concentration threshold for cocaine abuse treatment efficacy?
What molecular mechanisms underlie desipramine's effect on dopamine transporter inhibition in cocaine addiction?
How does desipramine compare to other norepinephrine reuptake inhibitors in cocaine use disorder management?
Are there specific biomarkers that correlate with desipramine response in cocaine-dependent individuals?
What adverse event profiles have been observed with desipramine versus bupropion in stimulant use disorders?
Trial Locations
- Locations (1)
Friends Research Institute
🇺🇸Los Angeles, California, United States
Friends Research Institute🇺🇸Los Angeles, California, United States