Hibiscus Sabdariffa Extract Effect on Neuromuscular Performance After Intense Resistance Exercise: a Randomized, Placebo-controlled, Crossover Study
Overview
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Universidad de Granada
- Enrollment
- 25
- Locations
- 2
- Primary Endpoint
- Explosive strength
Overview
Brief Summary
Exercise-induced muscle damage (EIMD) is a transient problem that athletes face after performing more intense and/or prolonged exercise than they are used to. EIMD is accompanied by an increase in the production of reactive oxygen species and a decrease in the antioxidant capacity of the organism. This phenomenon decreases the performance capacity of athletes due to impaired muscle strength and range of motion. Among the strategies to reduce EIMD, the use of nutritional strategies rich in antioxidants such as polyphenols stands out. In this sense, the extract of Hibiscus sabdariffa is particularly rich in polyphenolic antioxidants, among which anthocyanins stand out. Previous studies have concluded that the administration of an extract of Hibiscus sabdariffa can prevent overtraining syndrome by reducing the levels of oxidizing agents and increasing the body's antioxidant defenses. However, despite the fact that Hibiscus sabdariffa extract has been shown to be safe for humans to ingest and have various health benefits, to our knowledge, no studies have evaluated its ability to minimize neuromuscular performance impairment that occurs after performing an intense session of strength training. Based on previous evidence, we hypothesize that supplementation with an extract of Hibiscus sabdariffa will improve neuromuscular performance after performing intense resistance exercise in young (18-35 years) and trained adults, with at least 1 year of experience training. strength. The design of this study is crossover, randomized and placebo controlled, where each individual will act as her own control. The neuromuscular performance parameters to be evaluated will be: i) explosive strength - main variable, in terms of countermovement jump height (CMJ); ii) the maximum dynamic force; and iii) the ability to change direction, all of them 24h and 72h after a high-intensity strength training session. If our hypothesis is confirmed, the results of our study would not only have an impact at a scientific level but also at a commercial level through the development of supplements and/or functional foods.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Prevention
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Masking Description
triple-blinded
Eligibility Criteria
- Ages
- 18 Years to 35 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age: 18-35 years.
- •Body mass index: 18.5-30 kg/m2
- •Be able to understand the instructions, objectives, and protocol of the study.
- •Trained in some force sports discipline ≥1 year prior to the study and accustomed to carrying out the exercises of the evaluation protocol.
Exclusion Criteria
- •History of a major adverse cardiovascular event, renal failure, cirrhosis, eating disorder, polycystic ovarian syndrome, weight control surgery, type 2 diabetes mellitus, or HIV/AIDS.
- •Any chronic pathology in which the intake of nutritional supplements is not recommended.
- •Any condition that, in the investigator's judgment, impairs the ability to participate in the study or represents a personal risk to the participant.
- •Use of medications that may affect the results of the study.
- •Unstable body weight for 3 months prior to study start (\>4 kg weight gain or loss)
- •Routine use of teas/infusions/supplements rich in polyphenols.
- •Pregnancy and lactation.
- •Active tobacco or illicit drug use or history of treatment for alcohol abuse.
- •To be on a special diet or prescribed for other reasons (eg celiac disease).
Outcomes
Primary Outcomes
Explosive strength
Time Frame: 1 day (24h) after a bout of an intense resistance exercise
It will be measured through the height of the countermovement jump (CMJ)
Maximal dynamic force
Time Frame: 1 day (24h) after a bout of an intense resistance exercise
It will be measured by means of a CMJ with a load
Ability to change direction
Time Frame: 1 day (24h) after a bout of an intense resistance exercise
It will be measured by means of a CMJ with a load
Secondary Outcomes
- Maximal dynamic force(3 days (72h) after a bout of an intense resistance exercise)
- Ability to change direction(3 days (72h) after a bout of an intense resistance exercise)
- Explosive strength(3 days (72h) after a bout of an intense resistance exercise)
Investigators
Francisco Javier Osuna-Prieto
Principal Investigator
Universidad de Granada