Better postoperative pain management with epidural dexmedetomidine versus buprenorphine
Phase 4
- Conditions
- Health Condition 1: null- ASA physicalstatus I &II posted for elective lower abdominal surgeries
- Registration Number
- CTRI/2018/02/011977
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.patients of ASA physical status I-II
2.Aged between 18 to 65 years of either sex.
Exclusion Criteria
1.Contraindications to regional anesthesia:
2.Raised ICT
3.Patients refusal
4.local site infection
5.coagulation abnormalities,
6.allergy to local anaesthetics (amide group),
7.previous spine surgeries / spine deformities
8.Morbidly obese patients
9.neurologic, psychiatric disease, severe renal or hepatic derangement
10.Patients with history of drug abuse.
11.History of allergy or contraindications to either Dexmedetomidine or buprenorphine .
12.Concomitant use of medications which may exaggerate the heart rate response of Dexmedetomidine including digoxin or β-adrenergic antagonists.
ï?¶Patients who are pregnant and lactating mothers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method analgesic effectivenessTimepoint: analgesic effectiveness
- Secondary Outcome Measures
Name Time Method sedation,nausea, vomiting, pruritis, other side effects and hemodynamicsTimepoint: heart rate, blood pressure and respiratory rate recorded every 5min for first 30 min, every 10min for next 30min, every 15min next 60min and at every 30mins for next 4 hours.