Effects of Epidural Anesthesia on Postoperative Diaphragmatic Dysfunction Determined by Point-of-Care Ultrasound of the Diaphragm in Patients Undergoing Major Abdominal Surgery

Phase 3

• Conditions: Major abdominal surgeryEpidural analgesiaPostoperative pulmonary complications; Abdominal surgery; Epidural analgesia; Postoperative complications

• Registration Number: TCTR20201226004
• Lead Sponsor: Research Fund, Faculty of Medicine, Chiang Mai University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-26
• Study Completion: 2021-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Age >18 years,
ASA I-III,
Elective major abdominal surgery

Exclusion Criteria

-Patients who refuse an informed consent for this research study
-History of diaphragmatic abnormality such as diaphragmatic eventration or paralysis
-History of phrenic nerve injury or palsy
-History of neuromuscular disease
-Cannot achieve correct diaphragm visualization
-BMI ≥ 35 kg/m2
-Aortic aneurysm surgery
-Preoperative intubation
-Being planned for postoperative intubation by surgical/anesthesia team
-Failure to extubate at the operating room
-Patients with systemic infection or sepsis

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of postoperative diaphragm dysfunction within 48 hours after surgery Occurrence of the event

Secondary Outcome Measures

Name	Time	Method
Incidence of postoperative pulmonary complications During admission (within 14 days) Occurrence of the event