TCTR20210323005尚未招募4 期
Effect of nefopam infusion for postoperative multimodal analgesia in patients with contraindication to NSAIDs who undergo unilateral total knee replacement under spinal anesthesia combined with adductor canal block and periarticular local anesthetic infiltration
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •1.Age 18 years old or more
- •2.Undergo unilateral TKA
- •3.ASA physical status I, II, III
- •4.Have a contraindication to NSAIDs (sulfonamide allergy, CAD, CVA, Creatinine Clearance less than 50 ml/min)
- •5.Able to use patient-controlled analgesia (IV PCA)
- •6.Understand the Thai language
- •7.Willing to enroll
排除标准
- •1.Have a contraindication to nefopam: epilepsy, monoamine oxidase (MAO) inhibitors user, selective serotonin reuptake inhibitor user, glaucoma
- •2.Have a contraindication to regional anesthesia
- •3.Liver disease (Child-Pugh classification B or C)
- •4.Allergy to the drugs used in the research protocol: fentanyl, morphine, lidocaine, bupivacaine, paracetamol, dexamethasone, gabapentin
- •5.Chronic opioid use, drug abuse
- •6.Long-term use of NSAIDs, other drugs that may interfere with the research result
研究者
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