French Validation of Schizophrenia Proneness Instrument- Child Youth
- Conditions
- Clinical High Risk for Psychosis (CHR)
- Registration Number
- NCT06649552
- Lead Sponsor
- Centre Psychothérapique de Nancy
- Brief Summary
The clinical concept of a at risk mental state of developing psychosis is based on the identification of attenuated psychotic symptoms during the prodromal phase of psychoses (Schmidt et al., 2015). Early detection and support of these symptoms can delay the risk of transition to a first psychotic episode (van der Gaag, van den Berg, \& Ising, 2019).
The Basic Symptom approach enables detection at the earliest stage of the prodromal phase. It postulates that subtle, subjective manifestations predating attenuated psychotic symptoms are present very early in the prodromal phase of psychosis and also have predictive value for the risk of developing psychosis (F. Schultze-Lutter, 2009). Basic symptoms are assessed using the Schizophrenia Proneness Instrument, available in an adult (SPI-A) and child/adolescent (SPI-CY) version. These scales are part of the international recommendations for the assessment of patients with a Clinical State at High Risk of Psychosis (CHR-P) (Schmidt et al., 2015; F Schultze-Lutter et al., 2015). The SPI-A is validated in French under the name "Outil d'Evaluation du Risque Schizophrénique version adulte (OERS-A)" (Schultze-Lutter et al., 2007. French translation by JR. Teyssier with the collaboration of F. Gamma and P. Loulergue), but no French version of the SPI-CY has yet been validated.
In collaboration with Dr. Frauke Schultze-Lutter, the investigators have recently published a French translation of the SPI-CY (Schizophrenia Predisposition Instrument - Version for Children and Adolescents, F. Schultze-Lutter, M. Marshall, E. Koch, 2021. French translation by F. Bernardin and C. Dondé). This French translation must now be validated to ensure the inter-rater fidelity of the interview.
We therefore propose to study the inter-rater reliability of the French version of the SPI-CY by comparing ratings between clinicians who have undergone training in basic symptoms and in administering the SPI-A and SPI-CY tools by Dr. Schultze-Lutter. This validation will be carried out by comparing, on the one hand, the rating of the SPI-CY by a clinician A who has administered it to the patient and, on the other hand, the blind rating of a clinician B on the basis of the interview recorded by clinician A with his patient.
The investigators will also explore the links between the SPI-CY and other clinical scales such as the Multisensory Hallucination SCale (MHASC) (Demeulemeester et al., 2015), the Prodromal Questionnaire 16 (PQ-16) (Lejuste et al., 2021), the Audiograph (Giersch, Huard, Park, \& Rosen, 2021) and the Perceptual and Cognitive Aberrations (PCA) (McDonald et al., 2019).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 52
Not provided
- Pregnant woman, parturient or nursing mother
- Person deprived of liberty by judicial or administrative decision
- Person in a life-threatening emergency
- Impairment of the subject that makes it difficult, if not impossible, to participate in the trial or to understand the information provided.
- Abuse or dependence on any substance according to DSM V criteria, excluding cannabis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method SPI-CY assessment : Schizophrenia Proneness Instrument - Child and Youth version Day 1
- Secondary Outcome Measures
Name Time Method PQ16 assessment : Prodromal Questionnaire 16 Day 15 maximum Audiograph : formalization of visual hallucinations Day 15 maximum PCA assessment : Perceptual and Cognitive Aberrations Day 15 maximum MHASC assessment : Multisensory HAllucination SCale Day 15 maximum CAARMS assessment : Comprehensive Assessment of At Risk Mental State Day 15 maximum
Trial Locations
- Locations (3)
CHRU Lille
🇫🇷Lille, France
Centre Psychothérapique de Nancy
🇫🇷Nancy, France
CH Alpes-Isère
🇫🇷Saint-Egrève, France