The neural mechanisms involved in curiosity and uncertainty reductio
- Conditions
- gezonde breinnvt
- Registration Number
- NL-OMON32982
- Lead Sponsor
- niversiteit Leiden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 24
Adults subjects (18-30 years of age) with no history of neurological disorder/disease and no counter-indications to MRI will be included in this study. All participants will be right-handed native Dutch speakers with normal vision or contact lenses
Potential participants will be prescreened for contraindications for fMRI, which include metal implants, heart arrhythmia, claustrophobia, and possible pregnancy. They will additionally be prescreened for head trauma, history of neurological or psychiatric illness and/or use of psychotropic medications. Because of the difficulties in interpreting cognitive studies in subjects with Dutch as a second language, only native-Dutch speakers will be asked to participate in the study. Finally, left-handed individuals will be excluded from the study because some left-handers have substantially different brain organization relative to right-handers.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters are the significant clusters of brain activation<br /><br>associated with uncertainty and those associated with uncertainty reduction.<br /><br>The main behavioral study parameter is the number of items recalled in the free<br /><br>recall test as a function of condition (prior uncertainty vs. no prior<br /><br>uncertainty; see section 4). </p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>