The effect of 1 % chlorhexidine gel compared to 0.12% chlorhexidine gel-toothpaste or regular toothpaste or 0.2% chlorhexidine mouthwash in a 3-day non-brushing model on plaque accumulation.
- Conditions
- gingivitisinflammation of the gingiva
- Registration Number
- NL-OMON31135
- Lead Sponsor
- niversiteit van Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
* * 18 years
* Systemically healthy
* * 20 teeth
* 5 teeth per quadrant
* No pockets >5 mm.
* No orthodontic appliances
* No removable (partial) dentures
Exclusion Criteria
* Use of medication possibly influencing normal gingival health
* Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Quigley & Hein plaque index assessed after 3 days of *de novo* plaque<br /><br>accumulation.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Bleeding on marginal probing index and VAS-questionnaire</p><br>
Related Research Topics
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What molecular mechanisms underlie 1% chlorhexidine gel's anti-plaque efficacy compared to 0.12% formulations?
How does 1% chlorhexidine gel compare to 0.2% mouthwash in reducing gingivitis-related plaque in non-brushing models?
Which oral microbiome biomarkers predict response to chlorhexidine gel formulations in plaque control?
What adverse effects are associated with 3-day chlorhexidine gel use in gingivitis patients, and how are they managed?
Are there synergistic effects of combining chlorhexidine gels with essential oil-based toothpastes for plaque inhibition?