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Clinical Trials/NCT01294930
NCT01294930
Completed
Not Applicable

Indicators of Operative and Postoperative Complications in Patients Operated for Hip Fracture

University Hospital, Linkoeping1 site in 1 country45 target enrollmentJanuary 2011
ConditionsHip Fracture

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hip Fracture
Sponsor
University Hospital, Linkoeping
Enrollment
45
Locations
1
Primary Endpoint
mortality
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

Patients operated for hip fractures are older and have several conditions that have negative influences on the perioperative and postoperative prognosis.

Hip fractures can also be painful, which is stressful for the physiology of the patient. Many old patients have received to little fluid intake. They often have diuretic therapy, which even worsens dehydration/hypovolemia.

Some patients have to wait several days for surgery. Several studies have shown a high degree of complications and an increased mortality in this patient group.

Early preoperative optimization can improve the outcome. The available methods for optimization of the patient are complicated and time consuming.

The investigators wish with this study to try new approaches to find which patients still are dehydrated when they come to the operation ward.

The aim is to measure the color and density of the urine as well as to register the the variability in the plethysmographic curve before spinal anaesthesia.

These results will be compared to circulatory instability during and after surgery as well as to postoperative complications.

Detailed Description

All patients with hip fractures planed fore surgery at the Hospital in Norrkoping will come into consideration to participate in study. Many will however not be able to give consent. These will not be included in the study. Directly preoperatively urine will be collected. Color and density will be measured/registered. The pulseoximeter reading will be registered (Saturation, pulse, PI and PVI) before spinal anaesthesia and after spinal anaesthesia as well as during the surgery. Two to three days postoperatively a follow up will be performed, to register complications (Circulatory instability, confusion, infection, affected kidney function/creatinine rise). 30 day postoperative mortality will also be controlled. These results will be compared, to see if pulse oximeter readings or urine concentration can predict complications.

Registry
clinicaltrials.gov
Start Date
January 2011
End Date
July 2012
Last Updated
13 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Linkoeping
Responsible Party
Principal Investigator
Principal Investigator

Joachim Zdolsek

MD, PhD

University Hospital, Linkoeping

Eligibility Criteria

Inclusion Criteria

  • patients with hip fracture
  • operation for the hip fracture
  • informed consent

Exclusion Criteria

  • patients not giving consent
  • patients not being able to understand information

Outcomes

Primary Outcomes

mortality

Time Frame: 30 days

30-day mortality related to indices of dehydration (urine and pulse oximetry)

Secondary Outcomes

  • operative and postoperative complications(3 days)

Study Sites (1)

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