Heart and Renal Failure in Hip Fracture Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hypotension
- Sponsor
- Sahlgrenska University Hospital, Sweden
- Enrollment
- 105
- Locations
- 1
- Primary Endpoint
- Mortality
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as well as renal failure noted by Changes in Serum Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP
Detailed Description
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as awell as renal failure noted by Changes in S Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as a step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP
Investigators
Bengt Nellgard
Associate professor
Sahlgrenska University Hospital, Sweden
Eligibility Criteria
Inclusion Criteria
- •Hip fracture patient to be operated upon Classified as being ASA 3 or more
Exclusion Criteria
- •Not forfilling inclusion Criterias
Outcomes
Primary Outcomes
Mortality
Time Frame: 90 days
post surgery
Secondary Outcomes
- Serum concentrations of Troponin, NTproBNP, Creatinin and Cystatin C(90 days)