Effect of Intravenous Fentanyl Versus Intravenous Fentanyl and Paracetamol on Hemodynamic Response to Laryngoscopy and Endotracheal Intubation : A Prospective Randomized Double Blind Interventional Study at SMS Medical College Jaipur
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Mean Systolic Blood Pressure
研究概览
简要总结
The hemodynamic response to laryngoscopy and tracheal intubation in most patients are transient, highly variable, and probably of little consequences but may have adverse effects like arrhythmias, myocardial ischemia, left ventricular failure, increased intracranial pressure, and rupture of cerebral aneurysm on patients with pre-existing cardiovascular disease and cerebrovascular disease. In this study we will compare the effectiveness of intravenous fentanyl versus a combination of intravenous fentanyl and paracetamol on hemodynamic responses to laryngoscopy and endotracheal intubation under general anaesthesia
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing to give written informed consent.
- •Patient posted for elective surgeries under General anaesthesia ASA physical status classification 1 & 2.
排除标准
- •Patients with predictive difficult intubation such as short neck Patient with mallampatti class III AND IV Weight more than 90 kg Pregnant women Lactating women.
结局指标
主要结局
Mean Systolic Blood Pressure
时间窗: 1 min , 2 min , 4 min , 6 min , 10 min
Mean Diastolic Blood pressure
时间窗: 1 min , 2 min , 4 min , 6 min , 10 min
Mean of Mean arterial pressure
时间窗: 1 min , 2 min , 4 min , 6 min , 10 min
Mean Heart Rate
时间窗: 1 min , 2 min , 4 min , 6 min , 10 min
次要结局
- To determine the difference in percentage in cases who develop side effect in both group(Up to 12 hours of extubation)
研究者
Dr Sunil Chauhan
SMS medical college and hospital