The role of exhaled nitric oxide in patients with chronic obstructive pulmonary disease undergoing abdominal surgery

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease; Post-operative complications following abdominal surgery; Respiratory - Chronic obstructive pulmonary disease; Surgery - Other surgery

• Registration Number: ACTRN12616000211460
• Lead Sponsor: Faculty of Medicine, University of Thessaly

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients scheduled for major abdominal surgeries that were evaluated from an experienced physician were enrolled for the study.
The inclusion criteria are:
- age 18-75 years
- a diagnosis of COPD according to the American Thoracic Society (ATS) criteria in a stable condition and free from exacerbations in the preceding four weeks
- ASA physical status II, III, IV
- Smoking patients

Exclusion Criteria

Patients with:
- other organ failure
- cancer
- inability to cooperate
- patients with a recent exacerbation (e.g. requiring hospitalization or oral corticosteroids)
- patients with another or coexisting respiratory disorder (e.g. COPD and bronchiectasis)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of this study was to evaluate the relationship between exhaled NO in COPD patients undergoing major abdominal surgeries and the risk of presenting postoperative complications<br>The postoperative complications as laryngospasm, bronchospasm, cough, dyspnea and tachypnea will be assessed using clinical examination combined with the recorded use of corticosteroids and bronchodilators. <br>The values of blood gases 1 and 3 hours postoperatively as well 3 days after surgery will be recorded using a blood gas analyzer. [Perioperatively and 1-3 days postoperatively]