Topical Antibiotics for Prevention of Intensive Care Unit (ICU) Central Line Infections
Not Applicable
Withdrawn
- Conditions
- Blood Stream InfectionsSkin Diseases, Infectious
- Interventions
- Other: Petroleum Jelly
- Registration Number
- NCT00990392
- Lead Sponsor
- Fraser Health
- Brief Summary
The purpose of the study is to determine if the overall central venous catheter related infection rate can be reduced by the application of Polysporin Triple Therapy ointment to the insertion site.
- Detailed Description
Previous studies in the dialysis population have found a reduction in local and system central venous catheter related infections with the application of topical antibiotics to the insertion point. One such study found a mortality benefit with Polysporin Triple Therapy ointment. We intend to determine if this preparation can reduce overall line infection rates in the ICU environment through its application at the time of line insertion and twice more the following week.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- all patients admitted to the ICU requiring a central venous catheter
Exclusion Criteria
- previous line infection during same ICU stay
- CVC for hemodialysis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Petroleum Jelly Petroleum jelly Polysporin Triple Therapy Polysporin Triple Therapy ointment Polysporin Triple Therapy ointment applied to the insertion point at the time of CVC placement and twice within the first week.
- Primary Outcome Measures
Name Time Method Overall number of line related infections (local and blood borne) 6 months
- Secondary Outcome Measures
Name Time Method Length of hospital stay 7 months Prevalence of methicillin-resistant Staphylococcus Aureus (MRSA) 12 months Length of ICU stay 7 months
Trial Locations
- Locations (1)
Royal Columbian Hospital
🇨🇦New Westminster, British Columbia, Canada