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临床试验/NCT01115218
NCT01115218已完成不适用

The Influence of Anterior Chamber Fluid Mediators on the Success Rate of Trabeculectomy

University of Cologne1 个研究点 分布在 1 个国家目标入组 62 人开始时间: 2009年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
62
试验地点
1

研究概览

简要总结

The aim of the study is to investigate whether it is possible to predict the success of trabeculectomy in patients with glaucoma through the examination of mediators of wound healing in anterior chamber fluid. The success rate of trabeculectomy with mitomycin C in the literature is about 75%. This leads on the question why 25% of the patients received trabeculectomy are not sufficient treated and have not a long-term IOP reduction. Precisely this question is to be examined by the study.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients with glaucoma with a trabeculectomy required
  • 60 eyes of 60 patients, The ratio of female / male is not involved.
  • Eye pressure under local therapy: 20mmHg and above (corrected with pachymetry table).
  • age of at least 18 years

排除标准

  • all patients not included in the group of inclusion criteria.
  • less than 50yl anterior chamber fluid could be collected during the operation.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Arno Hueber

Arno Hueber

University of Cologne

研究点 (1)

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