The Effect Of Platelet Rich Fibrin on Implant Stability
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Implant Stabilitty Quotient (ISQ) evaluation: analysis of the resonance frequency values 4 week period.
研究概览
简要总结
The purpose of this study was to evaluate the effects of (Platelet Rich Fibrin) PRF application on implant osseointegration in the early phase of healing.
详细描述
Objectives:Achieving accelerated implant osseointegration could provide immediate or early loading of implants. Platelet-rich fibrin (PRF) is widely used to accelerate soft and hard tissue healing. Activated platelets in PRF release growth factors resulting in cellular proliferation, collagen synthesis and osteoid production. The aim of this study was to compare the stability of dental implants inserted with one-stage surgical protocol with or without PRF application.
Design: Non-randomized, Active Controlled Trial. Material and Methods: Twenty healthy patients (n=10 test group, n= control group) with adequate alveolar bone, having 2 or more adjacent missing teeth, extracted at least 6 months ago were included in this study. Minimum two tapered implants (Ankylosis, DentsplyFriadent) were placed to each patient. After surgical preparation of implant sockets, PRF that was prepared preoperatively was placed randomly to one of the sockets (PRF+). Acellular plasma portion of PRF was used to wet the implant placed into the PRF-coated socket. Resonance frequency measurements were made by Osstell ISQ after placement of implants, at 1 week and one month postoperatively.
Key Words: Dental implant stability, Platelet Rich Fibrin, Resonance frequency analysis
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The absence of any lesions in the oral cavity, and sufficient residual bone volume to receive two or more adjacent implants of ≥3.5 mm in diameter and 11.0 mm in length, and extracted at least 6 months ago.
排除标准
- •Insufficient bone volume
- •Parafunctional habits
- •Smoking more than 10 cigarettes per day
- •Excessive consumption of alcohol
- •Localized radiotherapy of the oral cavity
- •Antitumor chemotherapy
- •Liver, blood, and kidney diseases
- •Immunosuppression
- •Current corticosteroid or bisphosphonate use
- •Pregnancy
- •Mucocutaneous diseases involving oral cavity
- •Poor oral hygiene
结局指标
主要结局
Implant Stabilitty Quotient (ISQ) evaluation: analysis of the resonance frequency values 4 week period.
时间窗: Resonance frequency measurements were made by Osstell ISQ after placement of implants, at 1 week and one month postoperatively.
The stability of the implants were evaluated with the resonance frequency analysis (RFA) method. The measurements were carried out with Osstell ISQ (Implant Stability Quotient) (Osstell, Göteborg, Sweden) by connecting the transducer (smartpeg) to the implant. Two mesio-distal and bucco-lingual measurements were recorded and mean ISQ values were calculated. The resonance frequency measurements were repeated at first and fourth weeks.
次要结局
- Evaluation of osseointegration in different types of bone(Resonance frequency measurements in different bone types were made by Osstell ISQ after placement of implants, at 1 week and one month postoperatively.)
研究者
ELİF ONCU
Assist.Prof.Dr.
Necmettin Erbakan University