ADAMTS-13 Activity, Von Willebrand Factor and Platelet-Monocyte Aggregation in Patients Undergoing Percutaneous Coronary Intervention
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 11
- 试验地点
- 2
- 主要终点
- relationships between ADAMTS-13 activity, von Willebrand factor antigen and platelet-monocyte aggregates levels
研究概览
简要总结
The purpose of this research is to determine the relationship between proteins and enzymes in the blood and how they work with platelets to form blood clots in patients with coronary artery disease. The investigators hypothesize that the relationship between these factors could potentially be useful in identifying patients at higher risk for heart attacks.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Admission to hospital with suspected index event of Non-ST-Elevation Myocardial Infarction (NSTEMI), Unstable Angina (UA) or Stable Angina (SA)
- •Planned percutaneous coronary intervention during admission
排除标准
- •Recent history (< 6 months) of an acute coronary syndrome (other than current admission) or stroke
- •Recent history (< 6 months) of major surgery, trauma or thromboembolic event
- •Percutaneous coronary or peripheral intervention or any stent placement performed within the past 6 months
- •Current evidence of infection
结局指标
主要结局
relationships between ADAMTS-13 activity, von Willebrand factor antigen and platelet-monocyte aggregates levels
时间窗: change from baseline to after percutaneous coronary intervention
Assess the relationships between ADAMTS-13 activity, von Willebrand factor antigen and platelet-monocyte aggregates levels in subjects with coronary artery disease prior to and after undergoing PCI in this exploratory study
次要结局
未报告次要终点
研究者
Professor Noel Caplice
Professor, Cardiovascular Sciences
University College Cork