A Study to determine if improving sleep abnormalities can improve altered cognition among epilepsy patients.
- Conditions
- Health Condition 1: null- Epilepsy
- Registration Number
- CTRI/2017/04/008359
- Lead Sponsor
- Department of Health and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 119
1. Consequent patients diagnosed as TLE, FLE and JME by a single investigator (the PI), based on clinical, EEG, video-EEG and neuroimaging features, will be recruited as cases.
1. if they have any additional epilepsy syndrome or if they cannot be classified into any of these categories;
2.if there is an established diagnosis of primary sleep disorders;
3.if there is a past history of prolonged status epilepticus which was followed by abrupt deterioration in sensorium and/or cognitive performance;
4.history of major traumatic brain injury, encephalitis or other neurological disorder with encephalopathy, after onset of epilepsy
5.if they suffer from cardiac arrhythmias or bronchial asthma or impaired renal or liver functions.
6.if they have severe mental subnormality (IQ <40).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitive performance. <br/ ><br>Quality of life.Timepoint: 6 Months
- Secondary Outcome Measures
Name Time Method REM sleep percentage <br/ ><br>Slow wave sleep percentage. <br/ ><br>50% or greater reduction in Seizure frequency <br/ ><br>Quality of sleep (Sleep efficiency) <br/ ><br>Change in daytime sleepiness (Epworth sleepiness scale) <br/ ><br>Timepoint: 6 Months