The effects of a progressive walking program and glucosamine supplementation in persons with symptoms of knee or hip osteoarthritis.

Completed

• Conditions: Knee or hip osteoarthritis; Musculoskeletal - Osteoarthritis

• Registration Number: ACTRN12607000159459
• Lead Sponsor: niversity of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-03-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

Experience pain in at least one knee or hip, - Experience morning stiffness in that knee or hip in the past month- Experience difficulty with performing activities of daily living such as rising from a chair, getting out of bed and other self-care activities- Plan to live in the Greater Brisbane area over the next 6 months- Not exercising more than 60 mins per week- Not allergic to shellfish.

Exclusion Criteria

Corticosteroid or viscosupplement injections in the previous 3 months- Secondary forms of OA in the study knee or hip- Chondrocalcinosis in the study knee or hip- Concomitant inflammatory arthritis or metabolic arthritis- Infected knees or hips- Having a co-morbidity precluding safe involvement in exercise - Living in a dependent environment such as a nursing home- Participation in another research study- Plans for surgery during the study period- For women, pregnant or planning to become pregnant over the next year- Receiving psychiatric or psychological treatment (counselling or pharmacological)- The inability to walk at least 15 minutes continuously.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain is measured with the self-report Western Ontario and McMaster Universities (WOMAC) pain subscale . Questionnaire is administered at rest, and following completion of a self-paced stepping test (SPS). [At baseline, 6, 12, 18, and 24 weeks.];Physical function is assessed by time taken to complete the SPS and scores on the Western Ontario and McMaster Universities (WOMAC) physical function subscale[At baseline, 6, 12, 18, and 24 weeks.];Stiffness is measured using the Western Ontario and McMaster Universities (WOMAC) stiffness subscale. <br>[At baseline, 6, 12, 18, and 24 weeks.]

Secondary Outcome Measures

Name	Time	Method
Phyiscal activity levels using Active Australia survey.<br>Psychosocial measures are measured (Arthritis Self-efficacy Scale, Physical Activty Benefits and Barriers Scale, Goldberg Depression and Anxiety Scale, Physical Activity Self-regulation Scale).[Baseline, 6, 12, 18, and 24 weeks.<br>];Pedometers measuring daily step counts <br>Completion of weekly log sheets to assess compliance with walking program and to track glucosamine sulphate supplementation and medication usage.<br>General feedback on satisfaction with and perceptions of the walking program as recorded by open-ended questions. [6, 12, 18, and 24 weeks.]