Assessment of Endometrial Pattern and Sub-endometrial Vascularity in ICSI Outcome
- Conditions
- Infertility
- Registration Number
- NCT03683771
- Lead Sponsor
- Aljazeera Hospital
- Brief Summary
Despite constant progress in in vitro fertilization (IVF) techniques and ovarian stimulation, pregnancy and embryo implantation rates remain modest . The phenomenon of embryo implantation depends both on the embryo itself and on endometrial receptivity
- Detailed Description
A favorable uterine medium is necessary for embryo implantation, but endometrial receptivity can be negatively affected by ovarian stimulation . Study of endometrial receptivity is especially limited in the context of IVF cycles .
Biopsy of the endometrium cannot be considered during the treatment, and this has encouraged the development and use of ultrasonography and Doppler-like non-invasive methods to evaluate ovarian response to the stimulation and uterine receptivity .
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 120
- Maternal age from 20 to 40 years. Women with BMI range from 20 - 35 Women diagnosed with primary infertility
Maternal chronic medical disorder (diabetes mellitus or hypertension). Women diagnosed with autoimmune diseases or antiphospholipid syndrome
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of patients who will have positive pregnancy rate within 2 months patients who will get pregnant in ICSI cycle with measuring their doppler indices before ovum pick up
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Kasralainy hospital
🇪🇬Cairo, Egypt
Algazeerah and Kasralainy hospital
🇪🇬Giza, Egypt