Brain and Genetic Predictors of Individual Differences in Pain and Analgesia
- Conditions
- Pain, Acute
- Registration Number
- NCT03781570
- Lead Sponsor
- Trustees of Dartmouth College
- Brief Summary
The purpose of the study is to gain a better understanding of pain processing in the brain. Our understanding of how pain is processed in the brain is limited. We are testing for individual differences in pain perception and emotion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 541
- Participants must be registered in the Colorado Community Twin Sample (CTS).
- Not being registered in the Colorado Community Twin Sample (CTS).
- Any MRI contraindications.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain Rating Scores Made on a Visual Analog Scale (VAS) Measured during pain tasks at a single 4 hour experimental session (within one month of screening completion). Self reported pain using a Visual Analogue Scale (VAS) ranging from 0-100 (with 0 representing "no pain at all" and 100 representing "most intense pain imaginable (in the context of the experiment)). Higher scores indicate more pain. 0 is the minimum value and 100 is the maximum value. This scale is used for both thermal and mechanical pain. Reported values reflect averages of VAS ratings for individual stimuli for each of thermal and mechanical pain.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Colorado, Boulder
🇺🇸Boulder, Colorado, United States
University of Colorado, Boulder🇺🇸Boulder, Colorado, United States