NCT02778568已完成不适用
Acute Cardiovascular Responses and Chronic Adaptations of Strength Exercise in Intermittent Claudication Patients
University of Pernambuco2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2010年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Change in blood pressure
研究概览
简要总结
The aim of this study was to analyze the effects of resistance exercise and training on cardiovascular function of peripheral artery disease patients.
详细描述
Several studies have shown that strength training can promote important benefits for the cardiovascular system in healthy subjects and patients with chronic diseases. However, the effects of resistance exercise on cardiovascular function in intermittent claudication patients are unclear. In addition, it also do not know the chronic effects on cardiovascular function in these patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Had a graded treadmill test that was limited by claudication (2 minutes)
- •Had an ankle brachial index <0.90
- •Had systolic blood pressure ,160 mmHg and/or diastolic blood pressure,105 mmHg
- •Were not performing any regular exercise program
- •Were not using antihypertensive medications affecting the heart rate (e.g., b-blockers and nondihydropyridine calcium channel blockers)
- •Were nonobese
- •Individuals who have not undergone bypass surgery or angioplasty least one year ago
排除标准
- •Had no symptoms related to myocardial ischemia during the treadmill test
- •Amputation
结局指标
主要结局
Change in blood pressure
时间窗: Change from baseline to 12 and 24 weeks
次要结局
- Change in Health related Quality of life(Change from baseline to 12 and 24 weeksBaseline, 12 wks and 24 wks)
- Change Serum Cholesterol(Change from baseline to 12 and 24 weeks)
- Change in body fat(Change from baseline to 12 and 24 weeks)
- Change in serum glucose(Change from baseline to 12 and 24 weeks)
- Change in Walking distance(Change from baseline to 12 and 24 weeks)
- Change in Muscle blood flow of limbs(Change from baseline to 12 and 24 weeks)
- Change in TNFalpha(Change from baseline to 12 and 24 weeks)
- Change in Score Short-physical performance battery(Change from baseline to 12 and 24 weeks)
研究者
Raphael M. Ritti Dias
Full Professor
University of Pernambuco
研究点 (2)
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