Cannabis for Obesity Trial

Phase 2

Not yet recruiting

• Conditions: Obesity
• Interventions: Drug: Cannabis; Drug: Placebo

• Registration Number: NCT06137365
• Lead Sponsor: University of Kentucky

Brief Summary

The goal of this study is to determine the initial efficacy of once daily oral cannabis for weight loss in obese individuals.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-11-13
• Study First Submitted QC: 2023-11-13
• Study First Posted: 2023-11-18
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-12
• Last Update Posted: 2025-03-17
• Study Start: 2025-05
• Primary Completion: 2026-01
• Study Completion: 2026-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Active	Cannabis	Cannabis "gummy", starting at 2.5 mg THC and increased weekly by 2.5 mg increments up to a maximum target dose of 15 mg THC, administered once daily for duration of 6-month trial participation.
Placebo	Placebo	Placebo cannabis "gummy", containing no active THC, administered once daily for duration of 6-month trial participation.

Primary Outcome Measures

Name	Time	Method
Weight change	weekly for duration of 6-month trial	measured in kg using digital scale