Detraining in People Living With HIV/AIDS

Not Applicable

Completed

• Conditions: Sarcopenia; Lipodystrophy Syndrome, HIV
• Interventions: Other: combined training

• Registration Number: NCT03075332
• Lead Sponsor: Universidade Federal do Rio Grande do Norte

Brief Summary

The goal of this study was to evaluate the effect of detraining in the components of physical aptitude of people living with HIV/Aids (PVHA).

Detailed Description

The study was experimental with a sample composed by an Experimental Group (EG) with 11 PVHA, under antiretroviral therapy and a Control Group (CG) with 10 individuals without the infection; all which were under medical release and insufficiently active. The body composition was evaluated through the DXA, as well as the cardiorespiratory aptitude through the ergometer and the strength of the upper and lower limbs through dynamometry. Both groups conducted interventions with concurrent training for 15 weeks and the interruption of exercise was evaluated after a period of 5 weeks.

Study Timeline

• Study Start: 2016-02-19
• Primary Completion: 2016-06-21
• Study Completion: 2016-07-23
• Status Verified: 2017-02
• Study First Submitted: 2017-02-09
• Study First Submitted QC: 2017-03-08
• Last Update Submitted: 2017-03-08
• Study First Posted: 2017-03-09
• Last Update Posted: 2017-03-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

• Group experience to have a diagnosis of at least 2 years living with HIV / AIDS being in clinical follow-up in the Specialized Attention Services in HIV / AIDS (SAE), using ART, TCD4 lymphocyte count equal to or greater than 500 copies / mm³, viral load Undetectable (≤ 50 copies / mm³)
• Group control without any diagnosis of HIV / AIDS or any other pathology. Both groups completed the exercise program with a minimum frequency of 75%.

Exclusion Criteria

• Both groups taking part in any physical exercise in time of detraining

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
protocol with physical exercise	combined training	Both groups underwent a combined training intervention consisting of aerobic and resisted exercises in the same training session

Primary Outcome Measures

Name	Time	Method
Capacity cardiorespiratory	21 weeks	ml (cardiorespiratory aptitude through the ergometer)

Secondary Outcome Measures

Name	Time	Method
test force	21 weeks	kg (strength of the upper and lower limbs through dynamometry)

Trial Locations

Locations (1)

Juliany de Souza Araujo; 🇧🇷 Parnamirim, RN, Brazil