Comparison of the effect of tow embryo transfer in the stage of blastocyst and sequential transfer of a cleavage-a blastocyst embryo on pregnancy outcomes Patients who are candidates for frozen embryo transfer and recurrent implantation failure; a randomized clinical trial
Phase 3
Recruiting
- Conditions
- Infertility.Female infertility
- Registration Number
- IRCT20110509006420N27
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 140
Inclusion Criteria
Candidates for frozen embryo transfer
Failure of more than 2 implants
The number of frozen embryos is at least four
Women under the age of 45
Exclusion Criteria
Uncontrolled endocrine diseases (diabetes, hyperthyroid and hypothyroid)
Egg donation
Uncontrolled autoimmune diseases (lupus and rheumatoid arthritis)
Severe uterine adenomyosis
Sever Asherman
Untreated hydrosalpinx
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: Sonography.
- Secondary Outcome Measures
Name Time Method Chemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: Through the measurement of BHCG.;Twin pregnancy. Timepoint: In the 6th week of pregnancy. Method of measurement: Observation of two gestational sacs in vaginal ultrasound.;The rate of premature abortion. Timepoint: Ten weeks after embryo transfer. Method of measurement: Absence of fetal heartbeat in sonography.;Ectopic pregnancy. Timepoint: After proving chemical pregnancy. Method of measurement: Not increasing beta hCG titer and not seeing pregnancy sac in vaginal ultrasound.