Correlation Of Genetics With Post Operative Nausea And Vomiting In Patients Undergoing Major Elective Surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/10/046211
- Lead Sponsor
- ok Nayak and associated hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Undergoing general anaesthesia for elective abdominal, gynaecological, ear, nose and throat surgeries
2)American Society of Anaesthesiologists physical status I-II
3)Patients of either sex older than 18 years
Exclusion Criteria
1)Pregnancy
2)Psychiatric illness or patients with mental retardation
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between post - operative nausea and vomiting and genotypes of 5-HTTLPR, rs 4795541Timepoint: 0 hours, 6 hours, 12 hours, 24 hours
- Secondary Outcome Measures
Name Time Method Correlation between different genotypes of 5-HTTLPR (rs 4795541 and rs25531) and amount of postoperative anti-emetic medications consumption <br/ ><br>-Correlation between genotypes of 5-HTTLPR, rs 4795541and rs25531) and Apfel score for risk of PONV <br/ ><br>Timepoint: 0 hours, 6 hours, 12 hours, 24 hours