Correlation study of genetic variations with the pregabalin as analgesic in patients with chronic low back pain.

Phase 4

Withdrawn

• Conditions: Chronic low back pain; Anaesthesiology - Pain management

• Registration Number: ACTRN12616001649404
• Lead Sponsor: Aristotle University of Thessaloniki, Greece

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-11-29
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1.Age 18-79 years
2.Patients with lumbar radicular pain for more than three months
3.Patients with disc prolapse, spinal stenosis or failed surgery in the lumbar spine
4.Patients with neuropathic pain which is certified both by the discovery of nerve damage points as weakness, numbness, hyperalgesia, allodynia and with a NRS score larger that 4/10.

Exclusion Criteria

1. Pain in the lumbar region stronger than the radicular pain
2. Significant motor deficits / disorders in urine bladder or bowel
3. Known depression with or without antidepressant treatment
4. Background of addiction or abuse
5. Current treatment with gabapentin, pregabalin or opioids
6. Diabetic or postherpetic neuropathy
7. Renal insufficiency, diabetes, congestive heart failure, thrombocytopenia.
8. Use of ACE inhibitors

Study & Design

• Study Type: Interventional
• Study Design: Not specified