Prophylactic Effect of Memantine on Chronic Migraine Headache

Phase 3

• Conditions: Migraine headache.; Migraine

• Registration Number: IRCT20191205045623N1
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

18 to 65 years old
Chronic migraine headache according to International Classification of headache

Exclusion Criteria

Pregnancy or breast-feeding
Renal or hepatic impairment or known cardiovascular disease
History of allergy to memantine and topiramate

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The severity of migraine headache attacks. Timepoint: This evaluation was performed at the beginning of the study, and the end of first, second, third and fourth months of the study. Method of measurement: Visual Analogue Scale.;The disability level of migraine headache attacks. Timepoint: This evaluation was performed at the beginning of the study, and the end of first, second, third and fourth months of the study. Method of measurement: Migraine Disability Assessment Test Survey (MIDAS).;The frequency of migraine headache attacks. Timepoint: This evaluation was performed at the beginning of the study, and the end of first, second, third and fourth months of the study. Method of measurement: Daily headache diary.;The duration of migraine headache attacks. Timepoint: This evaluation was performed at the beginning of the study, and the end of first, second, third and fourth months of the study. Method of measurement: Daily headache diary.