The effectiveness of the combination of Memantine and Betahistine on insomnia severity, quality of life and severity of symptoms in people with primary tinnitus
Phase 3
- Conditions
- Condition 1: Severity of tinnitus symptoms. Condition 2: Insomnia severity. Condition 3: Quality of Life.TinnitusInsomniaH93.1G47.0
- Registration Number
- IRCT20190427043389N4
- Lead Sponsor
- Zanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Having primary tinnitus for more than 3 months
Willingness and interest to participate in the study
Having moderate intensity of insomnia (scoring more than 15 based on the ISI Insomnia Severity Questionnaire)
Exclusion Criteria
Tinnitus due to anatomical disease
tumor
Previous use of memantine
History of high blood pressure
Suffering from chronic and debilitating diseases as diagnosed by the attending physician
Known mental illness
Concomitant use of medications that interact with memantine
contraindication of memantine by the doctors diagnosis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of tinnitus intensity. Timepoint: Before intervention and 3 months after the start of the intervention. Method of measurement: Tinnitus severity index standard questionnaire.
- Secondary Outcome Measures
Name Time Method Insomnia severity. Timepoint: Before the start of the intervention and 3 months after the start of the intervention. Method of measurement: ISI Insomnia Severity Index Questionnaire.;Quality of Life. Timepoint: Before the start of the intervention and 3 months after the start of the intervention. Method of measurement: Standard Quality of Life Questionnaire (SF-36).