Optimal dose of protamine for heparin reversal in open heart surgery

Not Applicable

Recruiting

• Conditions: protamine; cardiopulmonary bypass, Adult patient underwent cardiopulmonary bypass surgery; heparin&#44

• Registration Number: TCTR20151118005
• Lead Sponsor: Faculty of Medicine, Prince of Songkla University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-11-18
• Study Completion: 2016-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

Underwent cardipoulmonary bypass surgery

Exclusion Criteria

1.Renal failure
2.Liver failure
3.Redo surgery
4.Endocarditis
5.Thoracic aortic aneurysm
6.Cyanotic heart disease
7.Preoperative use anticoagulant
8.Use intraoperative or postoperative of intra-aortic balloon pump (IABP) or extracorporeal membrane oxygenation (ECMO)
9.Heparin resistance
10.Intraoperative death
11.Use total circulatory arrest technique
12. Incomplete data

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Protamine dose intraoperative and postoperative mg

Secondary Outcome Measures

Name	Time	Method
Activated clotting time intraoperative and postoperative second