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临床试验/NCT01161342
NCT01161342已完成不适用

Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition

Uppsala University0 个研究点目标入组 1,771 人开始时间: 2008年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
1,771
主要终点
All-cause mortality

研究概览

简要总结

The aim of the study is to estimate the prevalence of malnutrition among older adults admitted to hospital and to analyse predictive factors for malnutrition. Further, the aim was to analyse the association between nutritional status and all-cause and cause-specific mortality.

The hypothesis is that malnourished patients have a higher mortality then well-nourished patients after three years.

详细描述

The baseline survey was a cross-sectional study of 1771 patients aged ≥65 years who were admitted to hospital. Nutritional status was assessed using the MNA instrument, and possible risk factors associated with malnutrition were recorded during the hospital stay. All-cause mortality was followed up after median 3.5 years s in a cohort study of 1767 participants. Cause-specific mortality was followed up after median 4.7 years in a cohort of 1767 participants. Previous dietary intake in middle-aged and older adults was recorded at basline in 725 participants, who had their nutritional status assessed with the MNA when admitted to hospital 10 years later.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients 65 years or older

排除标准

  • unable to communicate and no relative could anwer the questions (n = 356)
  • receiving palliative care (n = 44)
  • impossible to measure height or weight (n = 22)
  • miscellanious (n = 71)

结局指标

主要结局

All-cause mortality

时间窗: All-cause mortality was analyzed after median 3.5 years.

Survival was calculated from the date of the MNA screening to the date of death.

Cause-specific mortality

时间窗: Cause-specific mortality was analyzed after median 4.7 years.

Survival was calculated from the date of the MNA screening to the date of cause-specific death.

Nutritional status according to the screening instrument Mini Nutritional Assessment (MNA)

时间窗: 30 minutes

\[The 18 questions in the MNA instrument are weighted, and the threshold values of the instrument categorize patients into three nutritional status groups: well-nourished (MNA score 24-30), at risk of malnutrition (MNA score 17-23.5), or malnourished (MNA score \<17).

次要结局

未报告次要终点

研究者

发起方
Uppsala University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Lisa Söderström

Med.lic.

Uppsala University

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