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Clinical Trials/NCT01161342
NCT01161342
Completed
N/A

Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition

Uppsala University0 sites1,771 target enrollmentMarch 2008
ConditionsMalnutrition

Overview

Phase
N/A
Intervention
Not specified
Conditions
Malnutrition
Sponsor
Uppsala University
Enrollment
1771
Primary Endpoint
All-cause mortality
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The aim of the study is to estimate the prevalence of malnutrition among older adults admitted to hospital and to analyse predictive factors for malnutrition. Further, the aim was to analyse the association between nutritional status and all-cause and cause-specific mortality.

The hypothesis is that malnourished patients have a higher mortality then well-nourished patients after three years.

Detailed Description

The baseline survey was a cross-sectional study of 1771 patients aged ≥65 years who were admitted to hospital. Nutritional status was assessed using the MNA instrument, and possible risk factors associated with malnutrition were recorded during the hospital stay. All-cause mortality was followed up after median 3.5 years s in a cohort study of 1767 participants. Cause-specific mortality was followed up after median 4.7 years in a cohort of 1767 participants. Previous dietary intake in middle-aged and older adults was recorded at basline in 725 participants, who had their nutritional status assessed with the MNA when admitted to hospital 10 years later.

Registry
clinicaltrials.gov
Start Date
March 2008
End Date
May 2009
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Uppsala University
Responsible Party
Principal Investigator
Principal Investigator

Lisa Söderström

Med.lic.

Uppsala University

Eligibility Criteria

Inclusion Criteria

  • Patients 65 years or older

Exclusion Criteria

  • unable to communicate and no relative could anwer the questions (n = 356)
  • receiving palliative care (n = 44)
  • impossible to measure height or weight (n = 22)
  • miscellanious (n = 71)

Outcomes

Primary Outcomes

All-cause mortality

Time Frame: All-cause mortality was analyzed after median 3.5 years.

Survival was calculated from the date of the MNA screening to the date of death.

Cause-specific mortality

Time Frame: Cause-specific mortality was analyzed after median 4.7 years.

Survival was calculated from the date of the MNA screening to the date of cause-specific death.

Nutritional status according to the screening instrument Mini Nutritional Assessment (MNA)

Time Frame: 30 minutes

\[The 18 questions in the MNA instrument are weighted, and the threshold values of the instrument categorize patients into three nutritional status groups: well-nourished (MNA score 24-30), at risk of malnutrition (MNA score 17-23.5), or malnourished (MNA score \<17).

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