跳至主要内容
临床试验/CTRI/2024/07/071591
CTRI/2024/07/071591尚未招募不适用

Platelet indices as unequivocal markers of active disease in patients of non-radiographic axial Spondyloarthritis: An observational study

Datta Meghe Institute of Higher Education and Rsearch1 个研究点 分布在 1 个国家目标入组 197 人开始时间: 2024年8月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
197
试验地点
1
主要终点
Platelet Indices Proving to be Reliable markers of active disease in Patients of non-radiographic axial Spondyloarthritis

研究概览

简要总结

The patients of spondyloarthritis including both non radiological axial SpA and Ankylosing Spondylitis will be included in this study as cases. Platelet indices in both these groups will be compared with existing markers of disease activity such as CRP and MRI pelvis. along with platelet indices, C3, ESR, Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio and CRP to albumin ratio will also be compared. same comparison will be done with the control group of normal individuals.

研究设计

研究类型
Observational

入排标准

年龄范围
16.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • All patients diagnosed with axial spondyloarthritis as per ASAS criteria above the age of 16 years and giving consent will be included in this study.

排除标准

  • Patients with metabolic disorders, recent pregnancy, known case of tuberculosis/brucellosis/Active infections, malignancy, trauma, crystal arthropathy, h/o vasculitis, h/o hemoglobinopathies, smokers, patients on antiplatelet drugs and patients not consenting will be excluded.

结局指标

主要结局

Platelet Indices Proving to be Reliable markers of active disease in Patients of non-radiographic axial Spondyloarthritis

时间窗: Baseline

次要结局

  • Biomarkers such as CRP to Albumin ratio, Platelet to lymphocyte ratio, Complement 3 as surrogate markers of disease activity in non radiographic axial Spondyloarthritis(Baseline)

研究者

发起方
Datta Meghe Institute of Higher Education and Rsearch
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Abhijeet Kumar Agrawal

Jawaharlal nehru medical college

研究点 (1)

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