Study conducted to see the effect of Gandhaka Druti Pichu and Yastimadhu Taila Pichu in Fissure.

Not yet recruiting

• Conditions: Acute anal fissure. Ayurveda Condition: PARIKARTIKA,

• Registration Number: CTRI/2022/05/042828
• Lead Sponsor: BVVS Ayurved Medical College and Hospital

Brief Summary

*Parikartika* is one of the most painful and commonest condition in *Gudagata Vikara*s affecting majority of the population in modern world. Acharya’s have explained it as one among the *Vamana Virechana Vyapat* and *Bastivyapat*. It is caused by *Sthana Samshraya* of vitiated *Vata & Pitta Dosha’s* in *Gudapradesh*, leading to *Kartanavat Vedana* and *Daha* in *Gudapradesh*. It can be correlated to fissure-in-ano based on signs and symptoms.

Fissure-in-ano is an elongated ulcer in longitudinal axis of lower anal canal associated with constipation, severe pain & burning sensation during defecation and bright red bleeding. In acute type pain is so severe that, patient develops fear for defecation and this further worsens the condition. Fissure-in-ano occurs most commonly in midline posteriorly, in males usually posteriorly 95%, anteriorly 5%, & in females posteriorly 80%, & anteriorly 20%. About 30–40% of the population suffers from proctologic pathologies at least once in their lives, in that anal fissure comprises of 10–15%. It occurs equally in both men & women and is common in all age groups especially adults of 15-40 years. The incident is supposed to be high in one who passes hard & dry stool.

In the *Chikitsa* of *Parikartika,* Acharyas have mentioned *Madhura, Kashaya Rasa Sneha Yukta Dravya’s* in the form of *Piccha Basti*, *Anuvasana Basti*, *Pichu, Varti & Lepa,* which pacifies *Vata* and *Pitta Dosha’s*. Acharya Sushrutha has mentioned *Anuvasana Basti* with *Grithamanda* & *Yastimadhu Taila* in *Parikartika.*

Acharya Sushrutha has mentioned *Pichu Prayoga* in the context of *Shashti Upakrama*, in the management of *Vrana*.

*Yastimadhu* *Taila* is having *Vata-Pittahara Guna*, *Sheeta Veerya,* which acts as *Dahaprashamaka* and *Vranaropaka*, hence it is taken as standard drug by previous research works done.

*Gandhaka Druti* is mentioned in Rasa Ratna Samucchaya in the context of *Uparasas*, It is *Taila* obtained of *Gandhaka*, which acts as *Vedanasthapaka* and *Vranaropaka,* so it has been selected in the treatment of *Parikartika*.

Hence the present study is under taken to evaluate and compare the efficacy of *Gandhaka Druti Pichu* and *Yastimadhu Taila* *Pichu* in the management of *Parikartika* w.s.r to Acute Fissure-in-Ano.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-05-25
• Study Start: 2022-05-31

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1.Patients diagnosed with Parikartika (acute fissure- in-ano) 2.Patients with diabetes and hypertension which are under control.

Exclusion Criteria

• Patients diagnosed with other co-existing Ano rectal diseases.
• Fissure in ano due to systemic disorders.
• Patients suffering from infectious diseases.
• Patients of chronic fissure in ano with sentinel pile.
• Pregnant women & lactating women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in pain, burning sensation, bleeding per rectum and constipation	15 Days

Secondary Outcome Measures

Name	Time	Method
Reduction in the size of ulcer.	Improvement in the wound healing

Trial Locations

Locations (1)

BVVS Ayurved Medical College and Hospital; 🇮🇳 Bagalkot, KARNATAKA, India

BVVS Ayurved Medical College and Hospital

🇮🇳Bagalkot, KARNATAKA, India

Dr Mahalaxmi Bilagi

Principal investigator

9902527344

mahalaxmibilagi9845@gmail.com