Molecular Characteristics of the Persistent Intestinal Fistulae After Glue Application

Completed

• Conditions: Enterocutaneous Fistulas

• Registration Number: NCT01990833
• Lead Sponsor: Jianan Ren

Brief Summary

For non-healing ulcers, abnormal periods of wound healing processes: inflammation, proliferation and remodelling, are believed to lead to chronic wounds. As a chronic "stalled" wound, investigators hypothesized that these glue-assisted closure (GAC)-failed enterocutaneous fistula (ECF) might have a prolonged inflammatory phase modulated by excessive pro-inflammatory cytokines or proteases. The aim of this study was to analyze the chemicals in ECF wounds in order to determine patients' condition and fitness for GAC.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01
• Primary Completion: 2013-03
• Study Completion: 2013-03
• Status Verified: 2013-11
• Study First Submitted: 2013-11-11
• Study First Submitted QC: 2013-11-21
• Last Update Submitted: 2013-11-21
• Study First Posted: 2013-11-25
• Last Update Posted: 2013-11-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• above 18 years old;
• single tubular (tract length >2 cm) ECF;
• low output volume (<200 ml/24h);

Exclusion Criteria

• fistulas of cancer-infiltrated;
• associated abscess;
• foreign bodies;
• distal bowel obstruction;

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fistula closure after glue application	7 days	No fistula output