SCFA production and their metabolic effects after inulin ingestion - Inulin and SCFA production

niversiteit Maastricht0 个研究点目标入组 15 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•Overweight/obese men (BMI>=25kg/m2<=35kg/m2)
•- Aged 20 - 50 years
•- Caucasian
•- Normal fasting glucose (plasma glucose < 6.1 mmol/L)
•- Normal blood pressure (systolic blood pressure 100-140mmHg, diastolic blood pressure 60-90 mmHg)
•- Weight stable for at least 3 months (± 2kg)

•- Type 2 diabetes mellitus (defined as FPG >= 7.0 mmol/l)
•- Gastroenterological diseases or abdominal surgery
•- Cardiovascular diseases, cancer, liver or kidney malfunction, disease with a life expectancy shorter then 5 years
•- Abuse of products
•- Plans to lose weight or following of a hypocaloric diet
•- Regular supplementation of pre- or probiotic products, use of pre- or probiotics 3 months prior to the start of the study
•- Intensive exercise training more than three hours a week
•- Use of any medication that influences glucose or fat metabolism and inflammation (i.e. NSAIDs).
•- Regular use of laxative products
•- Use of antibiotics 3 months prior to the start of the study

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