Effect of Antioxidant on Endurance Performance in Healthy Men
- Conditions
- Exercise Tolerance
- Interventions
- Other: placeboDietary Supplement: Oligomerized litchi fruit extractDietary Supplement: VItamin C + Vitamin E mixture
- Registration Number
- NCT00731926
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
oligomerized litchi fruit extract may enhance the submaximal endurance exercise performance
- Detailed Description
Regular physical exercise has many beneficial effects, but it has been reported that strenuous exercise could elevate the production of free radical and other reactive oxygen species (ROS) which eventually injure the tissues and decrease the muscle function.So many kinds of antioxidant supplementations have been tried to decrease the muscle fatigue and enhance the exercise performance. polyphenolic flavonoids abundant in fruits and leafy vegetables have strong antioxidant effect. oligomerized litchi fruit extract has strong antioxidant capacity and higher bioavailability compared to that of grape seed polyphenol. The aim of this study was to determine whether oligomerized litchi fruit extract could induce endurance exercise performance more than Vit C + Vit E mixture or placebo could do. Therefore, we designed double blind randomized controlled trial, setting the change of running time to exhaustion under submaximal treadmill test as the primary endpoint.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 69
- healthy men over 20 years old non-smoker
- BMI>25 or body fat>25% he who intakes the antioxidant supplement in recent 2 weeks
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 3 placebo - 1 Oligomerized litchi fruit extract - 2 VItamin C + Vitamin E mixture -
- Primary Outcome Measures
Name Time Method change of running time to exhaustion under 80% of maximal heart rate 1 month
- Secondary Outcome Measures
Name Time Method VO2max, anaerobic threshold 1 month