Autoantibodies Against Specific Cytokines in Adults With Severe Mycobacterial Infection

• Conditions: Mycobacterium Infection

• Registration Number: NCT01628744
• Lead Sponsor: China Medical University Hospital

Brief Summary

In adult, the prevalence of mycobacterial infections is increased with age is largely unknown. IFN-gamma-IL-12/23 axis or NF-kappaB pathways might also plays crucial roles in adult against mycobacteria. Based on this hypothesis, the investigators had applied a functional assay to these pathways in patients with mycobacterial infection.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Status Verified: 2012-06
• Study First Submitted: 2012-06-24
• Study First Submitted QC: 2012-06-26
• Last Update Submitted: 2012-06-26
• Study First Posted: 2012-06-27
• Last Update Posted: 2012-06-27
• Study Completion: 2014-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients with mycobacterial infection

Exclusion Criteria

• Malignancy
• Severe autoimmune
• HIV infection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Graduate Institute of Clinical Medical Science, China Medical University; 🇨🇳 Taichung, Taiwan