The Brain Health Study: A Pragmatic, Patient-Centered Trial
- Conditions
- DementiaAlzheimer Disease
- Interventions
- Other: Brain Health Assessment
- Registration Number
- NCT05905796
- Lead Sponsor
- University of California, San Francisco
- Brief Summary
The eRADAR Brain Health Study seeks to refine and test a novel, low-cost strategy for increasing dementia detection within primary care.
- Detailed Description
Detailed description: eRADAR stands for "electronic health record (EHR) Risk of Alzheimer's and Dementia Assessment Rule." It is a low-cost tool or algorithm that uses readily available EHR data elements to identify high-risk patients. The investigators will conduct a pragmatic randomized controlled trial to assess the impact of implementing eRADAR as part of a supported outreach process on dementia detection rates. The investigators will also explore the impact of eRADAR implementation on healthcare utilization and patient experience.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 1350
- No prior diagnosis of dementia (defined from EHR diagnosis codes) and not receiving medications for dementia
- Active patient at participating clinic
- Adequate data to calculate eRADAR score
- Currently receiving hospice care
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Brain Health Intervention Brain Health Assessment Calculate eRADAR scores using EHR data to identify eligible individuals Invite eligible individuals for brain health assessment visit Enter results of brain health assessment visit into EHR Provide summary of results and recommended next steps to the Primary Care Physician and participant
- Primary Outcome Measures
Name Time Method New dementia diagnosis 12 months after index date Rate of new dementia diagnosis identified from the electronic health record (EHR) using prespecified set of ICD-10 codes
- Secondary Outcome Measures
Name Time Method Number of dementia-related laboratory tests performed 6 months after index date Defined from EHR data
Number of specialty visits or referrals for dementia assessment 6 months after index date Defined from EHR data
Number of urgent care and emergency department visits 1 year after index date Defined from EHR data
Number of dementia-related neuroimaging tests performed 6 months after index date Defined from EHR data
New diagnosis of mild cognitive impairment 12 months after index date Rate of new diagnosis of mild cognitive impairment following the intervention, defined from EHR data
Number of inpatient days 1 year after index date Defined from EHR data
New dementia diagnosis (secondary definitions) 18 months after index date Rate of new dementia diagnosis identified from the electronic health record (EHR) using prespecified set of ICD-10 codes
Number of primary care visits 6 months after index date Defined from EHR data
Proportion of days covered for current prescriptions 1 year after index date Standard measure of medication adherence
Percent of participants who receive new medications for dementia 6 months after index date Defined from medication orders or dispensings in the electronic health record
Number of scheduled visits missed 1 year after index date Clinic "no shows"
Proportion of people offered a brain health visit who accept and attend the visit 3 months after invitation mailed Rate of accepting brain health visit
Positive predictive value of eRADAR algorithm 12 months after index date Proportion of people with a high risk eRADAR Score who attend a brain health visit who are diagnosed with dementia
Trial Locations
- Locations (3)
Division of General Internal Medicine
🇺🇸San Francisco, California, United States
Women's Health Primary Care
🇺🇸San Francisco, California, United States
UCSF Primary Care at China Basin
🇺🇸San Francisco, California, United States