The effectiveness of intravenous Lidocaine versus Morphine in pain management in acute critical limb ischemia
- Conditions
- acute pain in critical limb ischemia.Arterial embolism and thrombosis
- Registration Number
- IRCT201210148872N2
- Lead Sponsor
- Tehran University of Medical Sciences -Faculty of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria: having clinical signs and symptoms of acute critical limb ischemia which are known with 5P (Pain-paralysis – pulselessness- paresthesia- pallor) and is diagnosed by an emergency medicine specialist. Consent to join in the study is required and the form is read and signed by each one of the patients.
Exclusion criteria: contraindications of lidocaine and morphine: lung problems (including acute asthma; pulmonary edema); Heart conditions(including heart failure; cardiogenic shock; Block degree three; arrhythmia WPW and Stoke Adams syndrome); neurological problems(including seizures; changes in state of consciousness); chronic pain in another site; pregnancy; use of pain killers in recent week; allergy to lidocaine or morphine; addiction; prescription of opioid drugs intravenously by EMS or triage nurses; respiratory distress; blood pressure <100mmhg; trauma; altered level of consciousness; language problems and dementia.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain scoring. Timepoint: 0-15-30 Min after the begining of study. Method of measurement: visual analogue scale.
- Secondary Outcome Measures
Name Time Method Side effect. Timepoint: 0-15-30 min after the begining of study. Method of measurement: by name.;Blood pressure. Timepoint: 0-15-30 min after the begining of study. Method of measurement: mm/hg.;Heart rate. Timepoint: 0-15-30 min after the begining of study. Method of measurement: beats per min.;Pulse oximetry. Timepoint: 0-15-30 min after the begining of study. Method of measurement: %.