JPRN-UMIN000006415已完成未知
The Multicenter Study for Effects of Eplerenone on Cardiac Diastolic Dysfunction in Hypertensive Patients - The Multicenter Study for Effects of Eplerenone on Cardiac Diastolic Dysfunction in Hypertensive Patients (MELODY STUDY)
Graduate School of Medical Sciences, Kumamoto University0 个研究点目标入组 180 人开始时间: 2011年9月27日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 180
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 30years-old 至 85years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1.Patients with severe renal failure (Ccr<=50ml/mi. Kakuta Y et al. Clin Exp Nephrol. 2010,14(1):63-7.) 2.Serum potassium level is equal or more than 5.0 mEq/L 3.Patients with severe hepatic insufficiency (Child-Pugh Score class C) 4.Patients currently under treatment of Itraconazole, Ritonavir, or Nelfinavir. 5.Patients with hypertrophic obstructive cardiomyopathy, cardiac amyloidosis, cardiac sarcoidosis, connective tissue disease, or malignancy 6.Patients with evere valvular disease 7.Patients with secondary hypertension 8.Patients underwent operative treatment or coronary angioplasty in the past one month 9.Patients treated with eplerenone or spironolactone in the past three months 10.Women who are wising to be pregnant, or of childbearing potential 11.Patients whose physicians determined inadequate to participate the study
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