Effects of high amylose wheat flour on the metabolic health of healthy Australian adults

Not Applicable

• Conditions: metabolic health; Metabolic and Endocrine - Normal metabolism and endocrine development and function; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12616001289404
• Lead Sponsor: CSIRO

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-09-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Males and females aged 18-65 years, BMI between 18.5 and less than or equal to 27.5 kg/m2, Normal fasting blood glucose concentration of 3.5 - 5.5 mmol/

Exclusion Criteria

1. Known presence of diabetes
2. History of smoking in the past 6 months
3. Pregnant or lactating
4. Sufferers of bleeding disorders
5. Known food allergy, hypersensitivity or intolerance to wheat and/or starchy foods
6. Taking medications known to influence glucose tolerance or gastric emptying (oral contraceptives are excepted) such as the following lists which comprise the main classes of drugs prescribed for diabetes mellitus and those that alter gastric emptying respectively:
Diabetes mellitus: Biguanides;Sulphonylureas; Meglitinide derivatives; Alpha-glucosidase inhibitors; Thiazolidinediones (TZDs); Glucagonlike peptide-1 (GLP-1) agonists; Dipeptidyl peptidase IV (DPP-4) inhibitors; Selective sodium- glucose transporter-2 (SGLT-2) inhibitors; Insulins; Amylinomimetics; Bile acid sequestrants; Dopamine agonists
Gastric emptying: Atropine and anticholinergics; Certain antihistamines (diphenhydramine, promethazine); Tricyclic antidepressants; Phenothiazines; Sympathomimetics; Nitrites; anticholinesterases; Sedative hypnotics; Antacids
7. Persons considered by the investigator to be unwilling, unlikely or unable to comprehend or comply with the study protocol
8. Participation in another research study within 30 days preceding the start of this study
9. Known history or presence of gastrointestinal, renal or hepatic disease of any cause
10. Night shift workers

Study & Design

• Study Type: Interventional
• Study Design: Not specified