CTRI/2022/03/041551尚未招募未知
Comparison of diaphragmatic ultrasound
Raju shakya0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •(a) age > 18 years;
- •(b) mechanically ventilated for more than 48 hrs;
- •(c) clinical improvement of the underlying acute cause of respiratory failure;
- •(d) adequate cough reflex;
- •(e) absence of excessive and/or purulent tracheobronchial secretion;
- •(f) stable cardiovascular status
- •(i.e. heart rate <120 beats/min; systolic blood pressure : 90â??160 mmHg; &
- •no/minimal vasopressor use, i.e., dopamine or dobutamine <5 μg/kg/min or
- •noradrenaline <0.05 μg/kg/min);
- •(g) stable metabolic status (i.e. electrolytes and glucose within normal range,
- •body temperature <38 °C, hemoglobin >=8â??10 g/dL;
- •(h) adequate oxygenation (SaO2) >92 % with FiO2 <=0.5 or
- •PaO2/FiO2 >=150 mmHg, both with PEEP <=8 cmH2O;
- •(i) adequate pulmonary function (i.e., RR <=30 breaths/min with VT >=5 mL/kg ideal body
- •weight (IBW) and no significant respiratory acidosis; and
- •(j) Richmond Agitation and Sedation Scale score ranging between â??1 and +1
排除标准
- •(a) age <18 years;
- •(b) pregnancy;
- •(c) presence of thoracostomy, pneumothorax, or pneumomediastinum;
- •(d) presence of flail chest or rib fractures;
- •(e) neuromuscular disease;
- •(f) use of neuromuscular blockers in the previous 48 h of study; and
- •(g) history or new detection of paralysis or paradoxical movement of a single hemidiaphragm
- •on diaphragmatic ultrasonography.
研究者
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