Assessement of Hemodynamic Changes Associated With Uterine Displacement Using Noninvasive Cardiac Output Monitoring and Transthoracic Echocardiography:
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- Cardiac Output
研究概览
简要总结
There is currently little information regarding the hemodynamic differences in uterine displacement techniques. Previous studies examining the hemodynamic effects of uterine displacement maneuvers have focused on incidence of hypotension and use of ephedrine.
Noninvasive cardiac output monitoring (NICOM) and transthoracic echocardiography (TTE) are becoming popular techniques in anesthesiology because they can provide noninvasive, valid, and precise hemodynamic data.There has been no study specifically examining the hemodynamic differences between the uterine displacement techniques using NICOM or TTE. While all three uterine displacement techniques are recommended, whether one technique may maximize maternal cardiac output is currently unknown.
详细描述
Aortocaval compression is a well-recognized physiologic concern in pregnancy. The gravid uterus can compress the inferior vena cava, impeding venous return and thereby reducing stroke volume and cardiac output.
The 2014 Society for Obstetric Anesthesia and Perinatology consensus statement on the management of cardiac arrest in pregnancy, and the 2010 American Heart Association guideline on maternal cardiac arrest recommend relieving aortocaval compression during chest compressions by performing uterine displacement There is currently little information regarding the hemodynamic differences amongst the recommended uterine displacement techniques. Previous studies examining the hemodynamic effects of uterine displacement maneuvers have focused on incidence of hypotension and use of ephedrine.
Noninvasive cardiac output monitoring (NICOM) and transthoracic echocardiography (TTE) are becoming popular techniques in anesthesiology because they can provide noninvasive, valid, and precise hemodynamic data.There has been no study specifically examining the hemodynamic differences between the uterine displacement techniques using NICOM or TTE. While all three uterine displacement techniques are recommended, whether one technique may maximize maternal cardiac output is currently unknown.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy ASA physical status I-II
- •Term parturient
排除标准
- •Woman in labor
- •Presence of maternal medical conditions affecting the cardiovascular system (including preeclampsia, gestational hypertension)
- •Fetal anomaly or intrauterine growth restriction (< 25th percentile)
- •Maternal renal or endocrine disease
研究组 & 干预措施
One handed uterine displacement
Uterine displacement using one hand
干预措施: TTE / NICOM (Device)
two handed uterine displacement
Uterine displacement using two hands
干预措施: TTE / NICOM (Device)
30 degrees uterine displacement
Uterine displacement using a 30 degrees wedge
干预措施: TTE / NICOM (Device)
结局指标
主要结局
Cardiac Output
时间窗: 10 minutes
次要结局
未报告次要终点
研究者
Lawrence Ching Tsen
Associate Professor, Harvard Medical School
Brigham and Women's Hospital
