Influence of the transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients on sarcopenia

Recruiting

• Conditions: Muscle wasting and atrophy, not elsewhere classified, multiple sites; Other and unspecified cirrhosis of liver; M62.59; K74.6

• Registration Number: DRKS00024507
• Lead Sponsor: niversitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients with liver cirrhosis and indication for TIPS placement
- Age = 18 years and < 85 years

Exclusion Criteria

- Non-cirrhotic indications for TIPS placement
Non-cirrhotic portal vein thrombosis
Budd-Chiari Syndrome
Nodular regenerative hyperplasia
- Age < 18 years and = 85 years
- Inability of the patient to consent
- Frustrated TIPS system
- Hepatocellular carcinoma (HCC)

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in sarcopenia in patients with advanced liver cirrhosis 12 months after TIPS placement

Secondary Outcome Measures

Name	Time	Method
- Change in sarcopenia in patients with advanced liver cirrhosis 6 months after TIPS placement<br>- To determine the prevalence of osteoporosis in patients with advanced liver cirrhosis presenting for the TIPS facility<br>- Change in osteoporosis in patients with advanced liver cirrhosis and initial diagnosis of osteoporosis at the time of TIPS placement 12 months after TIPS placement