PACTR202112813934276尚未招募3 期
Delayed Versus Immediate Use Of Zoledronic Acid For Postmenopausal Patients With ER/PR Positive Early Breast Cancer Who Are Using Adjuvant Letrozole
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- AUH
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 45 Year(s) 至 64 Year(s)（—）
- 性别
- Female
入选标准
- •1- Histologic evidence of ER/PR positive breast adenocarcinoma
- •2- Postmenopausal women.
- •3- Baseline LS and total hip BMD T-score > -2.0.
- •4- No prior treatment with denosumab or IV bisphosphonates is allowed.
- •5- No prior treatment with radiopharmaceuticals.
- •6- Not pregnant and not nursing.
- •7- Good dental health.
- •8- ECOG performance status 0-2.
- •9- Calculated creatinine clearance >= 30 mL/min.
- •10- Corrected serum calcium >= 8.0 mg/dL (2.00 mmol/L) and < 11.6 mg/dL (2.90 mmol/L)
排除标准
- •1- Patients with dental problems.
- •2- Patients with impaired renal functions
- •3- Patients with osteopenia, or T- score is below -2.0
- •4- Patients with history of serious drug hypersensitivity or drug allergy.
研究者
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