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Effect of scaling and root planing of teeth on systemic status of diabetics and non-diabetics

Not Applicable
Completed
Conditions
Health Condition 1: E119- Type 2 diabetes mellitus without complications
Registration Number
CTRI/2018/05/014037
Lead Sponsor
Amruta Joshi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
45
Inclusion Criteria

At least 20 functional teeth present.

Inclusion criteria for chronic periodontitis with type 2 DM group :

All patients diagnosed with chronic periodontitis according to the American Academy of periodontology 1999 criteria, with a >= 3mm mean clinical attachment loss and mean

interproximal probing depth (IPD) >= 5mm on two non-adjacent sites with a confirmed

diagnosis of Type 2 DM for >1 year, with no change in their diabetic treatment plan in

the previous 2 months, with no major diabetic complication and not on insulin therapy.

Inclusion criteria for chronic periodontitis without type 2 DM group :

Subjects diagnosed with chronic periodontitis according to the American Academy of

Periodontology 1999 criteria, with a >= 3mm mean clinical attachment loss and mean

interproximal probing depth (IPD) >= 5mm on two non-adjacent sites with no systemic

involvement.

Inclusion criteria for healthy controls group :

Subjects with Plaque index(PI) < 1, Gingival index(GI) < 1, Papillary bleeding index

(PBI) < 1, mean probing depth(PD) <3mm.

Exclusion Criteria

1) Subjects who have received any form of periodontal therapy, surgical or non-surgical

within past 6 months.

2) Subjects who have received antibiotic and or anti-inflammatory therapy within the past

6 months.

3) Subjects wearing orthodontic or prosthetic appliances.

4) Immunologically and systemically compromised subjects other than those with Type 2

DM.

5) Subjects who give present or past history of drug abuse, smoking.

6) Subjects with a habit of mouth breathing.

5

7) Subjects with lip piercing, tongue piercing.

8) Physically debilitated and mentally retarded subjects.

9) Pregnant women and lactating mothers.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
to evaluate the effect of non-surgical periodontal therapy on systemic <br/ ><br>inflammatory markers and metabolic control in subjects with chronic periodontitis with and <br/ ><br>without type 2 DM.Timepoint: Baseline, 3 months
Secondary Outcome Measures
NameTimeMethod
To evaluate the effect of non-surgical periodontal therapy on the clinical periodontal <br/ ><br>parameters in chronic periodontitis patients with and without Type 2 diabetes mellitus.Timepoint: zero and 3 months
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