To Compare and evaluate the effect of Nonsurgical periodontal therapy on serum levels of DNA sensing inflammasomes Absent in Melanoma 2(AIM2) Interferon ? inducible protein(IFI16) Cytokine interleukin(IL18) in Stage III periodontitis with and without Type 2 Diabetes Mellitus
- Conditions
- Health Condition 1: E119- Type 2 diabetes mellitus without complications
- Registration Number
- CTRI/2024/06/068456
- Lead Sponsor
- Ranjeet Deshmukh Dental College and Research Centre Digdoh Hills Hingna road Nagpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Group I Periodontally healthy patients presence of good oral hygiene with no visual signs of gingival inflammation bleeding on probing(BOP) in less than equal to 1 probing depth(PPD) less than equal to 3 mm
Group II Stage III periodontitis with a minimum of 15 teeth having PPD and clinical attachment level of greater than equal to four mm.
Group III Stage III periodontitis with T2DM PPD and CAL greater than equal to four mm. HbAonec levels in between 6.5 to 8 percentage
1 Patients who have undergone any periodontal therapy in the past 6 months
2 Patients with systemic diseases other than diabetes
3History of any medication including antibiotic treatment within the previous 3 months or regular use of specific drugs known to affect periodontal tissues
4 Pregnant women and lactating mothers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method