The influence of surgical interventions with and without cardiopulmonary bypass on Ca2+ signalling in alveolar macrophages
Completed
- Conditions
- Pulmonary dysfunction after surgeryRespiratoryPostprocedural respiratory disorders
- Registration Number
- ISRCTN94348100
- Lead Sponsor
- Charite - University Medicine Berlin (Charite - Universitaetsmedizin Berlin) (Germany)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. Elective coronary bypass graft surgery
2. Elective panendoscopy
3. Elective thoracic surgery
Exclusion Criteria
1. Aged less than 18 years
2. Relevant pulmonary diseases with oxygenation deficit
3. Liver disease stage greater than Child B
4. Human Immunodeficiency Virus (HIV)-infection
5. Corticosteroid therapy
6. Organ transplantation
7. Perioperative infection
8. Chronic inflammatory disease
9. Pregnancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Calcium signal intensity, measured immediately preoperatively and after the surgical procedure.
- Secondary Outcome Measures
Name Time Method Postoperative pulmonary infection, measured on day of discharge.