Outcome analysis after surgical or interventional correction of an aortic coarctation in infants
- Conditions
- Q25.1Coarctation of aorta
- Registration Number
- DRKS00028157
- Lead Sponsor
- Päd. Kardiologie und Intensivmedizin, OE6730,Medizinische Hochschule Hannover
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 150
Age <12 months old
-The patients should have received both echos we plan to analyze and the their therapy at our institution.
Complex congenital heart defects such as:
Atrial Septal Defect
Atrioventricular Septal Defect
Double-outlet Right Ventricle
d-Transposition of the Great Arteries
Ebstein Anomaly
Hypoplastic Left Heart Syndrome
Pulmonary Atresia
Single Ventricle
Tetralogy of Fallot
Total Anomalous Pulmonary Venous Return
Tricuspid Atresia
Truncus Arteriosus
Ventricular Septal Defect
These defects would make the speckle tracking analysis impossible to perform. Furthermore they are often simultaniously surgically repaired, thus not allowing us to study isolated effects of the coarctation correction.
-> Should we have enough* neonates (<30 days old) with isolated aortic coartcation we would like to mostly focus on them, since this is the most typical and most critical in terms of complications and clinical manifestation.
* we defined enough as a number of patients that would allow us to also perforn statistical analysis on the collected data. After a power calculation we came up with a number of min.20 patients: at least 10 Patients per group.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method longitudinal, radial and circumferential left-ventricular strain and longitudinal right-ventricular strain
- Secondary Outcome Measures
Name Time Method advanced echocardiographic parameters such as: LVEF, FAC, different diameters and wall thicknesses and different velocities measured at different segments of the aorta etc.