Comparative Evaluation of the effect of Non-Surgical Periodontal Therapy on systemic inflammatory markers and metabolic control in Patients with Chronic Periodontitis with and without Type II Diabetes Mellitus.

Amruta Joshi0 个研究点目标入组 45 人开始时间: 待定最近更新: 2021年11月24日

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•At least 20 functional teeth present.
•Inclusion criteria for chronic periodontitis with type 2 DM group :
•All patients diagnosed with chronic periodontitis according to the American Academy of periodontology 1999 criteria, with a >= 3mm mean clinical attachment loss and mean
•interproximal probing depth (IPD) >= 5mm on two non-adjacent sites with a confirmed
•diagnosis of Type 2 DM for >1 year, with no change in their diabetic treatment plan in
•the previous 2 months, with no major diabetic complication and not on insulin therapy.
•Inclusion criteria for chronic periodontitis without type 2 DM group :
•Subjects diagnosed with chronic periodontitis according to the American Academy of
•Periodontology 1999 criteria, with a >= 3mm mean clinical attachment loss and mean
•interproximal probing depth (IPD) >= 5mm on two non-adjacent sites with no systemic
•involvement.
•Inclusion criteria for healthy controls group :
•Subjects with Plaque index(PI) < 1, Gingival index(GI) < 1, Papillary bleeding index
•(PBI) < 1, mean probing depth(PD) <3mm.

•1) Subjects who have received any form of periodontal therapy, surgical or non-surgical
•within past 6 months.
•2) Subjects who have received antibiotic and or anti-inflammatory therapy within the past
•3) Subjects wearing orthodontic or prosthetic appliances.
•4) Immunologically and systemically compromised subjects other than those with Type 2
•5) Subjects who give present or past history of drug abuse, smoking.
•6) Subjects with a habit of mouth breathing.
•7) Subjects with lip piercing, tongue piercing.
•8) Physically debilitated and mentally retarded subjects.
•9) Pregnant women and lactating mothers.

发起方

Amruta Joshi